Dosage guide

AOD-9604 Dosage

hGH fragment

AOD-9604 has no approved therapeutic dose, and the reason matters: its human obesity program did not establish an effective weight-loss dose in the first place. The compound is a fragment of human growth hormone (hGH 176-191), and its fat-oxidation effects come from mouse studies rather than positive human efficacy trials.[1][2]

Reviewed for accuracy · Last reviewed July 7, 2026

Dosing

Injection (subcutaneous)~300 mcg, once daily (community-cited)
Typical cycle lengthVariable; no established regimen
There is no approved therapeutic dose. This figure is community practice; the human trials did not establish an effective weight-loss dose.

Community protocols commonly cite around 300 mcg injected subcutaneously once daily, often before fasted cardio, but this is convention rather than a validated regimen. The pooled human data (six randomized, placebo-controlled trials, roughly 900 subjects) was collected to characterize safety, and it did not demonstrate meaningful weight loss, so no dose there can be called effective.

FAQ

What is a typical AOD-9604 dose?Community protocols cite around 300 mcg once daily by injection. There is no approved or clinically validated dose, and the human obesity trials did not establish an effective weight-loss dose.
Why isn't there an established effective dose?Because the human program did not show meaningful weight loss versus placebo at the doses studied. Without a demonstrated effect, there is no basis for calling any particular dose effective.

References

  1. Safety and Tolerability of the Hexadecapeptide AOD9604 in HumansJournal of Endocrinology and Metabolism · 2013 · DOI 10.4021/jem157w
  2. Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragmentInternational Journal of Obesity and Related Metabolic Disorders · 2001 · PMID 11673763 · DOI 10.1038/sj.ijo.0801740
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This page is an independent educational reference and is not medical advice, and does not indicate any approval status for any use. Talk to a doctor before starting any compound.