The approved weight-management product (Zepbound) starts at 2.5 mg once weekly and increases no sooner than every four weeks to a maximum of 15 mg once weekly. The dual GLP-1/GIP agonist SURMOUNT-1 obesity trial studied 5 mg, 10 mg, and 15 mg once-weekly doses reached through a 20-week escalation.[1][2]
Reviewed for accuracy · Last reviewed July 7, 2026Example only, for a vial mixed to 5 mg/mL (e.g. 10 mg peptide + 2 mL BAC water). Recalculate for your own vial and water amount with the reconstitution calculator.
At the example 5 mg/mL concentration. For any other mix, use the calculator.
Because tirzepatide is sold commercially as a fixed-dose pen, people sourcing it as a vial usually need to convert milligrams into insulin-syringe units themselves. The chart below is worked at one example concentration; recalculate for your own vial with the calculator.
This page is an independent educational reference and is not medical advice. Talk to a doctor before starting or adjusting any compound.