Tesofensine has no approved label, so every dose figure here traces back to its Phase 2 TIPO-1 obesity trial rather than a prescribing guideline. That trial tested once-daily oral doses of 0.25 mg, 0.5 mg, and 1 mg alongside an energy-restricted diet over 24 weeks.[1][2]
Reviewed for accuracy · Last reviewed July 8, 2026Tesofensine has no approved label, so these figures describe what the Phase 2 TIPO-1 trial studied, not a recommendation. It was given orally once daily:
Weight loss in the trial was dose-related, but so was the rise in heart rate, which is one reason the higher doses were viewed cautiously. Because tesofensine is still investigational and never gained approval, treat these numbers as a description of what was studied, not a recommendation.
This page is an independent educational reference and is not medical advice, and does not indicate any approval status for any use. Talk to a doctor before starting any compound.