Dosage guide

Thymosin Alpha-1 Dosage

Immune-modulating peptide

The dose figures here trace back to published chronic hepatitis B trials rather than a US prescribing label, because thymosin alpha-1 is not FDA-approved in the United States. Those trials commonly used 1.6 mg given subcutaneously twice weekly, typically for around 26 weeks.[1]

Reviewed for accuracy · Last reviewed July 8, 2026

Dosing

The most commonly studied clinical regimen in chronic hepatitis B trials is a fixed subcutaneous dose given twice weekly, typically for about 26 weeks:

SettingStudied regimen
Chronic hepatitis B (trials)1.6 mg subcutaneous, twice weekly
Typical course length~26 weeks (6 months)
This describes the regimen used in published hepatitis B trials, not a recommendation for research use. Approval status and dosing differ by country.

Treat this as a description of the studied clinical regimen, not a recommendation for research use. Approval status, indications, and dosing vary by country, and the underlying trial base for hepatitis B is small, so the numbers should be read cautiously.

FAQ

What thymosin alpha-1 dose was used in hepatitis B trials?The commonly studied regimen was 1.6 mg subcutaneous twice weekly, usually for about 26 weeks. There is no US prescribing dose because it is not FDA-approved in the United States.
Is that dose a recommendation?No. It describes what published trials used. The evidence base is small and mixed, and approval and dosing differ by country, so treat it as descriptive rather than as advice.

References

  1. Comparison of the efficacy of thymosin alpha-1 and interferon alpha in the treatment of chronic hepatitis B: a meta-analysisAntiviral Research · 2008 · PMID 18078676 · DOI 10.1016/j.antiviral.2007.10.014
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This page is an independent educational reference and is not medical advice, and does not indicate any approval status for any use. Talk to a doctor before starting any compound.