A synthetic peptide fragment marketed as related to thymosin beta-4 (Tβ4), a tissue-repair protein, and used in community recovery protocols despite little human evidence.
Reviewed for accuracy · Last reviewed July 7, 2026TB-500 is a synthetic peptide sold as a recovery compound and marketed as related to thymosin beta-4 (Tβ4), a naturally occurring actin-binding protein involved in cell migration, angiogenesis, and tissue repair. A key honesty point: TB-500 is a fragment and is not structurally identical to full-length Tβ4, so evidence about Tβ4 does not automatically transfer to it.
The tissue-repair research that gets cited (wound healing, and cardiac repair after injury) was done on Tβ4 in animal models, not on TB-500 in humans. There are no controlled human trials of TB-500 for its marketed uses, it is not FDA-approved, and it is prohibited in drug-tested sport. Treat it as a research compound with a thin, indirect evidence base.
There is no established human dose. Community protocols cite roughly 2 – 2.5 mg once or twice weekly by injection, often stacked with BPC-157. TB-500 is not FDA-approved and is prohibited in drug-tested sport.
Read the full TB-500 dosage guide →There are no controlled human trials, so its safety profile is not characterized. Reported effects are mostly local or vague (injection-site irritation, occasional fatigue), and the honest caveat is that the human evidence is essentially absent.
Read the full TB-500 side effects guide →Keep unmixed vials refrigerated and away from light. Once reconstituted, most research reports store it refrigerated for roughly 4 weeks. See the full storage & safety guide for handling and disposal basics.
This page is an independent educational reference and is not medical advice, and does not indicate any approval status for any use. Talk to a doctor before starting any compound.