Dosage guide

NAD+ Dosage

Coenzyme (not a peptide)

Injectable NAD+ has no approved label and no validated dosing schedule, so every figure here describes what has been studied or marketed rather than a recommendation. One pilot study infused roughly 750 mg IV over 6 hours purely to measure how NAD+ moves through the body, not to test a benefit.[1][2][3][4]

Reviewed for accuracy · Last reviewed July 8, 2026

Dosing

There is no validated dosing schedule for injected NAD+. The figures discussed in research and clinic settings are not standardized and have not been shown to produce clinical benefit:

IV infusion (studied)~750 mg over ~6 hours in one pilot (pharmacokinetic study, not efficacy)
IV drips (clinic-marketed)Commonly cited ranges vary widely; not standardized or validated
Subcutaneous (marketed)Small self-administered amounts are described anecdotally; no validated protocol
These are descriptions of what has been reported or marketed, not a recommendation. Infusions are typically given slowly because faster rates are poorly tolerated.

Clinic-marketed NAD+ IV drips and subcutaneous protocols use ranges that vary widely and are not standardized or clinically validated. Infusions are commonly given slowly because faster rates are poorly tolerated. Because injected NAD+ is not an established therapy, treat any specific number as a description of practice, not a titration guideline.

This is separate from oral NAD+ precursors. Human trials of NMN (100 – 2000 mg/day) and NR show they raise blood NAD+ and are generally well tolerated, but those findings are about oral precursors and do not transfer to injected NAD+.

FAQ

What NAD+ dose is used in research?There is no validated dose. One pilot infused about 750 mg IV over 6 hours to study pharmacokinetics, not efficacy. Clinic drip and subcutaneous ranges vary widely and are not standardized.
Why are NAD+ infusions given slowly?Faster infusion is poorly tolerated. Small reports describe flushing, nausea, cramping, and chest pressure during infusion, so administration is commonly slowed to limit these effects.
Tracking a research protocol? PepHub can log doses and timing.Learn more →

This page is an independent educational reference and is not medical advice, and does not indicate any approval status for any use. Talk to a doctor before starting any compound.