Dosage guide

NAD+ Dosage

Coenzyme (not a peptide)

Injectable NAD+ has no approved label and no validated dosing schedule, so every figure here describes what has been studied or marketed rather than a recommendation. One pilot study infused roughly 750 mg IV over 6 hours purely to measure how NAD+ moves through the body, not to test a benefit.[1][2][3][4]

Reviewed for accuracy · Last reviewed July 8, 2026

Dosing

There is no validated dosing schedule for injected NAD+. The figures discussed in research and clinic settings are not standardized and have not been shown to produce clinical benefit:

IV infusion (studied)~750 mg over ~6 hours in one pilot (pharmacokinetic study, not efficacy)
IV drips (clinic-marketed)Commonly cited ranges vary widely; not standardized or validated
Subcutaneous (marketed)Small self-administered amounts are described anecdotally; no validated protocol
These are descriptions of what has been reported or marketed, not a recommendation. Infusions are typically given slowly because faster rates are poorly tolerated.

Clinic-marketed NAD+ IV drips and subcutaneous protocols use ranges that vary widely and are not standardized or clinically validated. Infusions are commonly given slowly because faster rates are poorly tolerated. Because injected NAD+ is not an established therapy, treat any specific number as a description of practice, not a titration guideline.

This is separate from oral NAD+ precursors. Human trials of NMN (100 – 2000 mg/day) and NR show they raise blood NAD+ and are generally well tolerated, but those findings are about oral precursors and do not transfer to injected NAD+.

FAQ

What NAD+ dose is used in research?There is no validated dose. One pilot infused about 750 mg IV over 6 hours to study pharmacokinetics, not efficacy. Clinic drip and subcutaneous ranges vary widely and are not standardized.
Why are NAD+ infusions given slowly?Faster infusion is poorly tolerated. Small reports describe flushing, nausea, cramping, and chest pressure during infusion, so administration is commonly slowed to limit these effects.
Tracking a research protocol? PepHub can log doses and timing.Download on the App Store

This page is an independent educational reference and is not medical advice, and does not indicate any approval status for any use. Talk to a doctor before starting any compound.