Dosage guide

IGF-1 LR3 Dosage

IGF-1 analog / research chemical

IGF-1 LR3 has never been studied in human clinical trials for muscle or performance use and is not FDA-approved, so there is no validated human dose to report. It is documented mainly as a laboratory cell-culture reagent, not a therapeutic.[1][2]

Reviewed for accuracy · Last reviewed July 8, 2026

Dosing

There is no validated human dose. IGF-1 LR3 has never been through human trials for muscle or performance use, so no clinical dosing exists to report:

Validated human doseNone established
Approved labelNone (not FDA-approved)
Figures circulating onlineAnecdotal, clinically unvalidated
Any microgram injection figures seen online are anecdotal reports, not a clinical guideline. We do not publish a titration table for a compound with no human trials.

You will find microgram injection figures for IGF-1 LR3 quoted on forums and vendor pages. Those are anecdotal, not a clinical guideline, and we do not reproduce them as a titration table because doing so would imply a validated protocol that does not exist. The honest reading is that any human dose is uncharacterized.

It is worth repeating that IGF-1 LR3 is not the approved IGF-1 product. Mecasermin (recombinant human IGF-1) has an approved pediatric indication and dosing, but it is a different molecule for a different purpose, and its dosing does not transfer to the LR3 research chemical.

FAQ

What is the correct IGF-1 LR3 dose?There is no correct or validated dose, because IGF-1 LR3 has no human clinical trials and no approved label. Any figures online are anecdotal and clinically unvalidated.
Can I use mecasermin dosing as a guide?No. Mecasermin is a different molecule (native recombinant human IGF-1) approved for a rare pediatric growth disorder. Its dosing does not apply to the IGF-1 LR3 analog.

References

  1. LONG R3 IGF-I Cell Culture Supplement (product and technical documentation)Repligen · current · Repligen product page, LONG R3 IGF-I
  2. Profile of mecasermin for the long-term treatment of growth failure in children and adolescents with severe primary IGF-1 deficiencyTherapeutics and Clinical Risk Management · 2009 · PMID 19707272 · DOI 10.2147/tcrm.s6178
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This page is an independent educational reference and is not medical advice, and does not indicate any approval status for any use. IGF-1 LR3 is a research chemical with no human trials. Talk to a doctor before considering any compound.