Dosage guide

GHK-Cu Dosage

Copper peptide

GHK-Cu dosing splits cleanly by route, and the evidence is very uneven between the two. The human data is almost entirely topical: cosmetic serums and creams use roughly 1 – 3% GHK-Cu once daily, and that is where the placebo-controlled facial studies sit. Injectable dosing is a different story.[1][2]

Reviewed for accuracy · Last reviewed July 7, 2026

Dosing

Topical (serum or cream)1–3%, once daily
Injection (subcutaneous)1–2 mg, once daily (community-cited; no clinical dosing data)
Typical cycle length4–8 weeks
The topical range reflects cosmetic-product formulations; the injection figures are community-cited only and are not backed by published human dosing studies.

Injectable GHK-Cu figures, commonly cited around 1 – 2 mg once daily over a 4 – 8 week cycle, are community-driven and are not backed by published human dosing studies. Treat them as anecdotal. One practical note: reconstituted GHK-Cu turns deep blue from the bound copper ion, which is normal and not a sign the peptide has degraded.

FAQ

What is a GHK-Cu dose?For topical use, cosmetic products use roughly 1 – 3% once daily, which is where the human evidence is. Injectable figures around 1 – 2 mg daily are community-cited only and are not supported by clinical dosing studies.
Why does reconstituted GHK-Cu turn blue?The blue comes from the copper ion bound to the peptide, since copper complexes are naturally blue. It is expected once dissolved and is not a sign of degradation.

References

  1. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin RegenerationBioMed Research International (Hindawi) · 2015 · PMID 26236730 · DOI 10.1155/2015/648108
  2. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene DataInternational Journal of Molecular Sciences (MDPI) · 2018 · PMID 29986520 · DOI 10.3390/ijms19071987
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This page is an independent educational reference and is not medical advice. Talk to a doctor before starting any compound.