An experimental small molecule (not a peptide) that activates estrogen-related receptors, studied as an exercise mimetic in mice, with no human data.
Reviewed for accuracy · Last reviewed July 7, 2026SLU-PP-332 is worth one clarification up front: it is not a peptide. It is a synthetic small molecule that activates the estrogen-related receptors (ERRα, ERRβ, and ERRγ, most potently ERRα), a family of receptors involved in energy metabolism. It is included here because it is widely searched alongside research peptides, but its chemical class is different.
It is studied as an exercise mimetic: in mice, it triggered an ERRα-dependent aerobic exercise gene program, increased oxidative muscle fibers and endurance, raised energy expenditure and fat oxidation, and improved insulin sensitivity in obese models. Every one of those findings is from mouse studies. There are no human trials, it is not FDA-approved, and it should be treated as an early-stage preclinical compound.
SLU-PP-332 has never been tested in humans, so there is no human dose. In mouse studies it was given orally. Any dosing figure online is extrapolation from animal research.
Read the full SLU-PP-332 dosage guide →Its side effects and safety in humans are entirely uncharacterized because there are no human studies. All effects reported to date, positive or otherwise, come from mice.
Read the full SLU-PP-332 side effects guide →As a preclinical research chemical, SLU-PP-332 has no consumer product guidance. Any handling would follow the supplier's research-use instructions. See the full storage & safety guide for general storage and safety basics.
This page is an independent educational reference and is not medical advice, and does not indicate any approval status for any use. SLU-PP-332 is a preclinical compound not tested in humans.