Sermorelin was historically dosed as Geref for growth-hormone-reserve testing and for pediatric growth-hormone deficiency. It is a synthetic GHRH (1-29) analog that stimulates the pituitary to release its own growth hormone. Today, compounded sermorelin has no current FDA-approved dosing label, so figures reflect historical clinical use and community practice.[1]
Reviewed for accuracy · Last reviewed July 7, 2026Community practice commonly cites roughly 200 – 500 mcg injected subcutaneously once daily, usually at night to line up with the body's natural overnight growth-hormone pulse. Because sermorelin works through the pituitary rather than supplying growth hormone directly, effects build gradually and taper after it is stopped.
This page is an independent educational reference and is not medical advice. Talk to a doctor before starting any compound.